Table 3.

Performance of models for overall survival.

Model name	Predictors involved	C-index (95% CI)
Training Cohort
Rad-signature	Six radiomics features	0.68 (0.62–0.74)
CRC model	Tumor number (<4/≥4), Rad-signature	0.73 (0.68–0.79)
Six-and-twelve	Sum of tumor size and number	0.64 (0.58–0.70)
Four-and-seven	Within four tumors and 7 cm (yes/no), Child-pugh class A/B	0.63 (0.58–0.68)
HAP	Albumin (≥36 g/dl/ <36 g/dl), AFP (≤ 400 ng/ml/> 400 ng/ml), bilirubin (≤ 17 μmol/l/ >17 μmol/l), tumor size (≤ 7 cm/>7 cm)	0.55 (0.50–0.61)
mHAP	All predictors involved in HAP score but bilirubin	0.59 (0.53–0.65)
mHAP-II	All predictors involved in HAP score plus tumor number (1 /≥2)	0.57 (0.52–0.63)
mHAP-III	Albumin, AFP, bilirubin, tumor size, and tumor number	0.54 (0.46–0.60)
ALBI grade	Albumin, bilirubin	0.52 (0.45–0.56)
Testing Cohort
Rad-signature	Five radiomics features	0.67 (0.56–0.79)
CRC model	Tumor number (<4/≥4), Rad-signature	0.70 (0.62–0.82)
Six-and-twelve	Sum of tumor size and number	0.64 (0.52–0.74)
Four-and-seven	Within four tumors and 7 cm (yes/no), Child-pugh class A/B	0.65 (0.55–0.75)
HAP	Albumin (≥36 g/dl/ <36 g/dl), AFP (≤ 400 ng/ml/>400 ng/ml), bilirubin (≤ 17 μmol/l/ >17 μmol/l), tumor size (≤ 7 cm/>7 cm)	0.55 (0.46–0.64)
mHAP	All predictors involved in HAP score but bilirubin	0.59 (0.47–0.71)
m-HAP-II	All predictors of the HAP score plus tumor number (1 /≥2)	0.61 (0.50–0.73)
mHAP-III score	Albumin, AFP, bilirubin, tumor size, and tumor number	0.58 (0.47–0.71)
ALBI grade	Albumin, bilirubin	0.56 (0.46–0.67)

C-index, Concordance index; CI, confidence interval; Rad-signature, radiomics signature; AFP, alpha-fetoprotein; CRC, combined radiomics-clinic; HAP, hepatoma arterial-embolization prognostic; ABLI, albumin-bilirubin.