TABLE 4.

Chemicals that may affect the expression of hub genes in pulmonary arterial hypertension.

Num.	Gene ID	Gene symbol	Gene name	Inference network	Inference score
1	9585	KIF20B	Kinesin Family Member 20B	Copper sulfate, epigallocatechin gallate, oxygen, quercetin, valproic acid	12.78
2	10592	SMC2	Structural maintenance Of chromosomes 2	4,4′-diaminodiphenylmethane, epigallocatechin gallate, quercetin, resveratrol, valproic acid	12.74
3	10733	PLK4	Polo like kinase 4	(+)-JQ1 compound, oxygen, paclitaxel, paraquat, resveratrol, silicon dioxide, valproic acid, vorinostat	22.45
4	54908	SPDL1	Spindle apparatus coiled-coil protein 1	Copper sulfate, methamphetamine, paraquat, resveratrol, smoke, valproic acid	3.85
5	55215	FANCI	Fanconi anemia complementation group I	Cobaltous chloride	3.83
6	55320	MIS18BP1	MIS18 binding protein 1	Copper sulfate, quercetin, resveratrol, valproic acid, vorinostat	15.25
7	79682	CENPU	Centromere protein U	Indomethacin	3.84
8	81930	KIF18A	Kinesin Family Member 18A	Amphetamine, copper Sulfate, epigallocatechin gallate, (+)-JQ1 compound, quercetin, resveratrol, silicon dioxide, valproic acid	24.22
9	259266	ASPM	Abnormal Spindle microtubule assembly	Cobaltous chloride	3.61