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. 2020 Jul 24;11:1134. doi: 10.3389/fphar.2020.01134

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Copyright © 2020 Pavlovskiy, Yashchenko and Zayachkivska

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Activities of Cystathionine-β-synthase (CBS) (A), Cystathionine-γ-lyase (CSE) (B) and Thiosulfate-dithiol sulfurtransferase (TST) (C) and changes of the oxidative index (D) in adult and aged rats (n = 5–6) fed with standard diet (SD) or high fructose diet (HFD) without and with H₂S releasing molecule compounds therapy (NaHS, ATB-340) and induction of acute stress (WIRS). Columns with whiskers (A, B, C) show mean ± standard deviation (SD). Box plots (D) show the median, lower, and upper quartile ranges, and the minimum and maximum values of the oxidative index of all groups; *p < 0.05 versus control.