Table 1.

Criteria used for semi-quantitative analysis of gastric mucosa damage.

Criteria	Score
The state of the epithelial layer on the degree of alteration	1—no changes; 2—desquamation of epithelium; 3—destruction of gastric foveoli; 4—hypertrophy and vacuolization of mucosa cells; 5—erosion
The state of subepithelial layer	1—no changes; 2—diffuse swelling of the submucosal basis; 3—pronounced uneven swelling of the submucosal base and insignificant infiltration; 4—severe swelling and disorganization of the submucosal basis; 5—perivascular hemorrhages
The epithelial layer leukocyte infiltration	1—no leukocyte infiltration; 2—moderate leukocyte infiltration; 3—average leukocyte infiltration; 4—severe leukocyte infiltration; 5—multiple leukocyte infiltrates

The measurement of GM damage was determined by protocol-blinded researchers. The number of animals showing these histopathological lesions in each group was compared with that of other groups.