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. 2020 Jul 17;8:640. doi: 10.3389/fcell.2020.00640

FIGURE 1.

FIGURE 1

Histological sections of the embryonic mouse lower jaw at the level of M1. The two odontogenic (white arrowhead) and osteogenic (black arrowhead) mesenchymal condensations are distant from each other being separated by a looser interstitial mesenchyme at embryonic day (ED)12.5 (A–C). Jaw bone appears at ED13.5 (D–F), and ED14.5 (G–I), and its development is accelerated on the lateral side (black arrowhead) when compared to the medial side (black arrow). Both the bone and tooth germ grow and approach each other at the expense of the area of the interstitial mesenchyme. The dental follicle cells achieve progressively a typical pattern (compare to Figure 2). Although mineralization will take place in both osteogenic and odontogenic condensations, the interstitial mesenchyme (see Figure 2) will never mineralize in normal conditions. * Refers to the Meckel’s cartilage, Bars = 100 mm (A,D,G) and 50 mm (B,C,E,F,H,I).