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Schematic diagram of engineered mesenchymal stem cells (eMSCs) therapy using supramolecular hyaluronic acid (HA) hydrogel. (A) Under ferric ions, Enhanced Green Fluorescent Protein (EGFP) or interleukin-12 mutant transgenes were transfected into MSCs via recombinant adenoviral (rAd) vectors. (B) Dexa-CB[6]/RA-DAH-HA hydrogel was synthesized by mixing CB[6]-HA solution and RA-DAH-HA solution with engineered MSCs and modular modification. Adapted with permission from Yeom et al. (2015).
