Table 3.

Fiber tracts associated with WMH lesion cluster

Contrast and Fiber Tract(s)	Hemisphere	Voxels	MAX (Z)	X (Voxel)	Y (Voxel)	Z (Voxel)
Stroop
CST, forceps major, inferior fronto‐occipital fasciculus, superior longitudinal fasciculus	L	1,704	0.99	116	54	88
*Forceps major	R	794	0.98	70	72	122
SDMT
CST, Forceps major	L	1,594	0.99	112	104	106
*Posterior corona radiata	R	1117	0.99	72	70	114
Posterior corona radiata	R	21	0.95	68	96	106
Splenium of corpus callosum	L	16	0.99	102	130	96
—	—	14	0.96	106	108	120
Digit Span
*Posterior corona radiata	R	153	0.98	50	64	106
Body of corpus callosum	L	11	0.97	102	130	96
Posterior thalamic radiation	R	11	0.96	58	68	102
MoCA
CST	L	13	0.99	112	104	106

Key(s): Voxels, number of voxel within cluster; MAX (Z), value of maximum z‐statistic; X/Y/Z (voxel), location of MAX (Z) voxel in MNI‐152 standard‐space coordinates (voxel).

Stroop, SDMT, Digit Span, and MoCA: lesion probability map results for the contrasts worse cognitive performance in PD^–WMH⁺ versus worse cognitive performance in PD^–WMH^–. Major fiber tracts passing through or (*) near the significant WMH lesion cluster.

Only clusters with ≥10 voxels are reported.