TABLE 2.
Control | PD | |||||
---|---|---|---|---|---|---|
Domain | Age at Baseline | Time from Baseline | Yearly Drop | Age at Baseline | Time from Baseline | Yearly Drop |
Orientation | −0.92 | −2.06 | 0.008 | −3.58*** | −4.77*** | 0.027 |
Executive/visuospatial | −3.62** | −2.28 | 0.030 | −4.81*** | −5.78*** | 0.063 |
Naming | −2.44* | −0.96 | 0.003 | −2.76* | −1.37 | 0.005 |
Attention | −1.48 | −1.35 | 0.014 | −2.78* | −5.14*** | 0.046 |
Language | −1.49 | −2.57* | 0.020 | −2.76* | −3.26** | 0.022 |
Abstraction | 01.42 | −0.21 | 0.001 | −1.76 | −1.58 | 0.008 |
Delayed recall | −4.40*** | −0.74 | 0.016 | −6.95*** | −0.87 | 0.015 |
Total | −5.06*** | −2.99** | 0.096 | −6.97*** | −4.70*** | 0.144 |
Reported results are the t statistics from the mixed effects model: Score ∼ 1 + Age at Baseline + Time from Baseline + (1|ID) as well as the estimated average yearly drop in each score for each group.
P < 0.01.
P < 0.001.
P < 0.0001.
MoCA, Montreal Cognitive Assessment Score; PD, Parkinson's disease.