Table 4.

Performances of CPIS for the diagnosis of VAP in patients with VA-LRTI

	CPIS value	Se	Sp	PPV	NPV	LR+	LR-	Youden index
Derivation cohort	≥ 5	0.83	0.51	0.66	0.72	1.68	0.34	0.34
	≥ 6	0.68	0.69	0.71	0.65	2.17	0.46	0.37
	≥ 7	0.51	0.88	0.83	0.61	4.13	0.56	0.39
Validation cohort	≥ 5	0.78	0.34	0.70	0.44	1.19	0.64	0.12
	≥ 6	0.60	0.70	0.80	0.48	2	0.57	0.3
	≥ 7	0.45	0.89	0.88	0.45	3.92	0.62	0.34

CPIS Clinical pulmonary infection score, Se Sensitivity, Sp Specificity, PPV Positive predictive value, NPV Negative predictive value, LR + Positive likelihood ratio, LR- Negative likelihood ratio