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. 2020 Jul 31;53(7):367–372. doi: 10.5483/BMBRep.2020.53.7.295

Fig. 1.

Fig. 1

CCRK is a crucial regulator for proper lung development. (A) Whole-mount lungs isolated from E12.5, E14.5, and E16.5 embryos. CcrkKO mutants showed fewer branching lobes and appeared smaller than their wild-type littermates. Scale bars = 1 mm. (B) Histological analysis of embryonic lung sections from indicated embryonic stages. Scale bars = 100 μm and 50 μm. (C) Images from whole-mount lungs isolated from E17.5 wild-type and Bromi−/− mutant embryos. (D) H&E staining of histological sections shows less saccule formation and thickening of the lung parenchyma in Bromi−/− mutants than in controls. Scale bars = 100 μm and 50 μm.