Table 2.
Laboratory findings of patients with COVID-19
| Normal Range | Total (539) | No-survivor (125) | Survivor (414) | P value | |
|---|---|---|---|---|---|
| WBC (× 109/L) | 3.5–9.5 | 5.41 (4.1–7.59) | 7.85 (4.74–12.01) | 5.07 (3.96–6.76) | < 0.001 |
| Neutrophils (× 109/L) | 1.8–6.3 | 3.54 (2.42–5.72) | 6.41 (3.77–10.97) | 3.08 (2.29–4.63) | < 0.001 |
| Lymphocytes (× 109/L) | 1.1–3.2 | 1.04 (0.76–1.5) | 0.69 (0.42–0.93) | 1.20 (0.88–1.63) | < 0.001 |
| Haemoglobin (g/L) | 115–150 | 126 (115–138) | 127 (113.5–139.5) | 126 (116–137) | 0.761 |
| Platelets (× 109/L) | 125–350 | 205 (151–261) | 172 (118–235) | 211 (163–271) | < 0.001 |
| CRP (mg/L) | 0–10 | 16.9 (5–61.3) | 70.5 (39.95–133.5) | 7.2 (5–37.95) | < 0.001 |
| PCT (ng/mL) | < 0.1 | 0.07 (0.04–0.25) | 0.21 (0.11–0.95) | 0.06 (0.03–0.12) | < 0.001 |
| CD3+ T cells (cells/μl) | 723–2737 | 667 (356–1010) | 277 (163.5–430) | 814 (516–1088) | < 0.001 |
| CD4+ T cells (cells/μl) | 404–1612 | 392 (200–586) | 172 (99.5–267.5) | 473 (291–657.75) | < 0.001 |
| CD8+ T cells (cells/μl) | 220–1129 | 221 (104–366) | 84 (39.5–155.5) | 262.5 (163–405.25) | < 0.001 |
| CD19+T cells (cells/μl) | 80–616 | 132 (82–202) | 88 (52–151) | 141 (96–219) | < 0.001 |
| CD16+ 56+ T cells (cells/μl) | 84–724 | 114 (70–190) | 79 (39–144) | 128.5 (79–210) | < 0.001 |
| IgG (g/L) | 7.0–16.0 | 12.2 (10.3–14.6) | 13.30 (10.75–16.95) | 11.95 (10.18–13.93) | < 0.001 |
| IgM (g/L) | 0.4–2.3 | 0.95 (0.70–1.3) | 0.94 (0.70–1.26) | 0.95 (0.69–1.31) | 0.658 |
| IgA (g/L) | 0.7–4.0 | 2.26 (1.74–3) | 2.54 (1.81–3.46) | 2.21 (1.73–2.89) | 0.012 |
| IgE (IU/ml) | < 100 | 52.3 (18.3–133) | 71.30 (30.2–214.5) | 42.25 (18.3–120) | < 0.001 |
| C3 (g/L) | 0.9–1.8 | 0.97 (0.82–1.1) | 0.89 (0.74–1.04) | 0.99 (0.84–1.13) | < 0.001 |
| C4 (g/L) | 0.1–0.4 | 0.241 (0.18–0.32) | 0.22 (0.159–0.30) | 0.24 (0.19–0.32) | 0.001 |
| Oximetry saturation (%) | 95–100 | 97 (92–98) | 90 (83–94) | 97 (95–98) | < 0.001 |
| Lactate (mmol/L) | 0.5–1.5 | 2 (1.5–2.53) | 2.40 (1.9–3.65) | 1.90 (1.43–2.38) | < 0.001 |
Data are median (IQR). WBC White blood cell, CRP C-reactive protein, PCT Procalcitonin, Ig immunoglobulins, C Complement proteins. P values were calculated by Mann-Whitney U test, χ2 test, or Fisher’s exact test, as appropriate. Statistical significance was determined at P<0.05