. 2020 Jul 6;18:558–570. doi: 10.1016/j.omtm.2020.07.001

Table 1.

Cardiac Functions of LV.LCR-EFS.hGAA-Treated Mice Compared to Wild-type or GAA^−/− Control Group

Parameters	Trend of Transplanted Animals Compared to	Statistical Significance
Cardiac output (mL/min)	WT = similar; GAA^−/− = lower	p = 0.59
Ejection fraction (%)	WT = similar; GAA^−/− = similar	p = 0.61
Fractional area shortening	WT = higher; GAA^−/− = lower	p = 0.40
Fractional shortening (%)	WT = lower; GAA^−/− = lower	p = 0.08
Stroke volume (μL)	WT = similar; GAA^−/− = lower	p = 0.10
End diastolic volume (μL)	WT = similar; GAA^−/− = lower	p = 0.29
End systolic volume (μL)	WT = similar; GAA^−/− = similar	p = 0.79
Ascending aortic diameter (mm)^a	WT = similar; GAA^−/− = lower	p = 0.12
Descending aortic diameter (mm)^a	WT = similar; GAA^−/− = lower	p = 0.16
Transverse aortic diameter (mm)^a	WT = similar; GAA^−/− = lower	p = 0.38
Ascending aortic velocity (mm/s)^a	WT = higher; GAA^−/− = lower	p = 0.06
Descending aortic velocity (mm/s)^a	WT = similar; GAA^−/− = lower	∗∗p = 0.0053
AV peak pressure^a	WT = higher; GAA^−/− = lower	p = 0.09
Early ventricular filling velocity (mm/s)	WT = similar; GAA^−/− = lower	p = 0.13
Late ventricular filling velocity (mm/s)	WT = lower; GAA^−/− = lower	p = 0.34
E/A	WT = higher; GAA^−/− = similar	p = 0.37
LV mass	WT = similar; GAA^−/− = lower	∗p = 0.014
Aortic root	WT = similar; GAA^−/− = lower	p = 0.13
LV posterior wall thickness (mm) diastole	WT = similar ; GAA^−/− = lower	∗p = 0.022
Interventricular septum (mm) diastole	WT = similar ; GAA^−/− = similar/lower	p = 0.51
LV internal dimension (mm) diastole	WT = similar ; GAA^−/− = similar	p = 0.83

E/A, E wave/A wave; LV, left ventricle.

Missing value