Figure 3.

BCL2L15 affected the signal transducer and activator of transcription (STAT)1 and STAT3 pathways. (A) The lentivirus specific for BCL2L15 and a negative lentivirus (shN) infected EECs for 48 h. EECs were treated with or without hormones followed by treatment with or without IFN-τ for 6 h or 12 h, and then collected for Western blotting. (B) EECs were treated with or without hormones followed by treatment with or without IFN-τ for 0, 1.5, 3, 6, 12, and 24 h, then collected for Western blotting. (C) The shBCL2L15 EECs were pretreated with or without fludarabine and Stattic, respectively. Then, the EECs were treated with hormones, followed by treatment with IFN-τ for 6 h or 12 h, and then collected for Western blotting. The data are presented as the means ± SEM of three independent experiments. * Significant difference (p < 0.05) compared with other groups; ** Significant difference (p < 0.01) compared with other groups