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. 2020 Jul 3;11(7):740. doi: 10.3390/genes11070740

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Comparison of LbCas12a and SpCas9 editing properties (the data from both serotonin transporters are summed together). (a) SpCas9 produces higher percentage of inserts in the outcomes of editing. (b) Average length of deletion is higher in embryos mutated by LbCas12a. (c) LbCas12a produces higher percentage of indels longer than 10 bp. (d) Both nucleases showed the same efficiency of editing.

Comparison of LbCas12a and SpCas9 editing properties (the data from both serotonin transporters are summed together). (a) SpCas9 produces higher percentage of inserts in the outcomes of editing. (b) Average length of deletion is higher in embryos mutated by LbCas12a. (c) LbCas12a produces higher percentage of indels longer than 10 bp. (d) Both nucleases showed the same efficiency of editing.