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. 2020 Jun 22;295(31):10741–10748. doi: 10.1074/jbc.AC120.013449

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© 2020 Kelly et al.

Published under exclusive license by The American Society for Biochemistry and Molecular Biology, Inc. This article is made available via the PMC Open Access Subset for unrestricted re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the COVID-19 pandemic or until permissions are revoked in writing. Upon expiration of these permissions, PMC is granted a perpetual license to make this article available via PMC and Europe PMC, consistent with existing copyright protections.

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Figure 4. — SAXS analyses. A, scattering profiles from laboratory-purified SAXS samples containing pseudoknots from SARS-CoV (blue) and SARS-CoV-2 (red). Inset, scattering profiles from inline SEC-SAXS measurements, containing purely monomeric pseudoknots. B and C, difference between the scattering profiles for SARS-CoV and SARS-CoV-2 pseudoknots obtained from lab-purified SAXS (B) and inline SEC-SAXS (C) samples. Arb., arbitrary.