Table 1.

Selected examples of medium-sized heterocycles obtained by intramolecular Heck reaction.

Entry	Product a	Reaction Conditions	Yields (%) (Examples) b	Ref.
1		cat. PdCl2(PPh3)2, K2CO3, EtOH, DMF, 100 °C, 2 h	52	[19]
2		cat. Pd(OAc)2, AcOK, TBAB, DMF, 100 °C, 4 h	60–86 (10)	[20]
3		cat. Pd(OAc)2, K2CO3, MeCN, 80 °C, 1 h	61–70 (4)	[21]
4		cat. Pd(OAc)2/PPh3, Cs2CO3, TBAC, DMF, 90 °C, 2 h	80–84%	[22]
5		cat. Pd(OAc)2, AcOK, TBAB, DMF, 100 °C, 4 h	79–91 (4)	[23]
6		cat. Pd(OAc)2, TEAC, Cy2NMe, DMA, 100 °C, 12 h	69	[24]
7		cat. Pd(OAc)2, Cs2CO3, TBAB, DMF, 100 °C, 12 h	59	[25]
8		cat. Pd2(dba)3.CHCl3, PPh3, NEt3, DMF, 130 °C	72	[26]
9		cat. Pd(OAc)2, NaHCO3, TBAC, DMF, 110 °C, 16 h	73–86 (2)	[27]
10		cat. Pd(OAc)2, TEAC, Cy2NMe, DMA, 95 °C, 6 h	72	[24]
11		cat. Pd(OAc)2, PPh3, NEt3, MeCN, MW (125 °C), 6 h	85	[28]
12		cat. Pd(OAc)2, AcOK, TBAB, DMF	80–85 (5)	[29]
13		cat. Pd(OAc)2/DavePhos, K2CO3, MeCN, 80 °C, 1 h	47	[30]
14		cat. Pd(OAc)2/JohnPhos, TBAA, DMF, 100 °C	60	[31]

^a The formed bond is indicated in magenta. ^b Number of examples.