Table 4.
Association analysis of the MMP1 x MMP12 interaction with non-contact ACL rupture (codominant model).
| MMP1 x MMP12 | rs2276109 | p * | |||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| TT | CT | CC | |||||||||||||||
| CON (n = 144) |
ACLR (n = 158) |
OR | 95% CI | CON (n = 55) |
ACLR (n = 63) |
OR | 95% CI | CON (n = 3) |
ACLR (n = 6) |
OR | 95% CI | ||||||
| rs1799750 | -- | 48 | 51 | 1.00 | NA | NA | 6 | 8 | 1.25 | 0.41 | 3.88 | 1 | 0 | 0.00 | 0.00 | NA | 0.412/ 0.347 |
| -G | 71 | 84 | 1.11 | 0.67 | 1.85 | 31 | 35 | 1.06 | 0.57 | 1.98 | 0 | 0 | NA | NA | NA | ||
| GG | 25 | 23 | 0.87 | 0.43 | 1.73 | 18 | 20 | 1.05 | 0.49 | 2.21 | 2 | 6 | 2.82 | 0.54 | 14.67 | ||
ACLR—anterior cruciate ligament rupture, CON—control; * p-values/p value adjusted for sex; OR—odds ratio, 95% CI—confidence intervals; NA—not applicable.