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. 2020 Jul 15;25(14):3227. doi: 10.3390/molecules25143227

Scheme 8.

Scheme 8

Michael cyclization of both stereoisomers of Passerini products 20a and 20b. * means both R and S diastereoisomers of 20a or 20b, which have been independently converted into 24/25 (anti-20a or anti-20b) and 26/27 (syn-20a or syn-20b).