Table 1.
Composition of fatty acids in hypothalamus and serum of young and aged mice.
| Fatty Acid (µg/g) | Hypothalamus | Serum | ||
|---|---|---|---|---|
| 4 Months (Young) |
24 Months (Old) |
4 Months (Young) |
24 Months (Old) |
|
| C14:0 (myristic acid) | 42.38 ± 3.11 1 | 55.51 ± 3.53 * | 4.02 ± 0.31 | 4.60 ± 0.55 |
| C16:0 (palmitic acid, mg/g) | 6.63 ± 0.16 | 7.21 ± 0.11 * | 0.47 ± 0.05 | 0.44 ± 0.03 |
| C16:1n7 (palmitoleic acid) | 213.03 ± 6.78 | 204.30 ± 4.35 | 45.43 ± 8.62 | 45.06 ± 5.77 |
| C18:0 (stearic acid, mg/g) | 5.61 ± 0.09 | 5.72 ± 0.04 | 0.19 ± 0.01 | 0.19 ± 0.01 |
| C18:1n9 (oleic acid, mg/g) | 6.15 ± 0.07 | 5.51 ± 0.03 *** | 0.22 ± 0.04 | 0.24 ± 0.02 |
| C18:2n6 (linoleic acid) | 200.00± 14.67 | 238.33 ± 5.55 * | 584.20 ± 71.75 | 515.85 ± 47.49 |
| C18:3n3 (α-Linolenic acid) | ND 2 | ND | 80.21 ± 5.10 | 74.94 ± 5.67 |
| C18:3n6 (γ-Linolenic acid) | 143.13 ± 13.58 | 202.73 ± 11.35 * | 9.76 ± 1.00 | 9.69 ± 0.85 |
| C20:0 (arachidic acid) | 78.10 ± 5.44 | 122.05 ± 6.68 ** | ND | ND |
| C20:3n6 (dihomo-γ-linolenic acid) | 105.32 ± 5.74 | 114.18 ± 3.25 | 22.97 ± 3.20 | 22.36 ± 2.60 |
| C20:4n6 (arachidonic acid, mg/g) | 3.68 ± 0.07 | 3.78 ± 0.33 | 0.15 ± 0.01 | 0.16 ± 0.01 |
| C20:5n3 (eicosapentaenoic acid) | 182.74 ± 11.32 | 218.70 ± 11.53 | 32.89 ± 0.30 | 26.99 ± 1.31 |
| C24:0 (lignoceric acid, mg/g) | 4.25 ± 0.10 | 4.43 ± 0.06 | 0.08 ± 0.009 | 0.07 ± 0.006 |
1 Mean ± standard deviation. 2 Not detected. * p < 0.05; ** p < 0.01; *** p < 0.001; compared to young group.