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The ipt1Δ and csg2Δ mutations causing defects in complex sphingolipid biosynthesis are suppressed by luteolin and iron salt, and negatively interact with vps13Δ. Growth of wild-type, vps13Δ (KJK181A), csg2Δ, ipt1Δ, and the respective double mutants on YPD plates containing SDS was compared by drop test. The effect of luteolin and FeCl2 on growth is also shown. Images were taken after 2 or 3 days of incubation.
