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. 2020 Jul 23;36:101652. doi: 10.1016/j.redox.2020.101652

Table 1.

Comparison of chemo sensitivity in sorafenib-sensitive and sorafenib-resistant cells with different mtTXNRD3 expression levels.

Compound Cell Lines & IC50 (Mean ± SD) p Value
Doxorubicin (μM)
 MV4-11 IC50 = 0.54 ± 0.11 MV4-11R
IC50 = 2.57 ± 0.16		 0.0004
SK-Hep1VC
IC50 = 0.99 ± 0.06
 SK-Hep1OE
IC50 = 3.42 ± 0.30
 0.0014
Ara-C (μM) MV4-11
IC50 = 0.86 ± 0.12		 MV4-11R
IC50 = 3.35 ± 0.18		 0.0003
SK-Hep1VC
IC50 = 0.56 ± 0.06		 SK-Hep1OE
IC50 = 1.48 ± 0.18		 0.0091

The data were the results of three separate experiments. Each experiment was done in triplicate. The statistical significance of the difference between sorafenib-sensitive (low mtTXNRD3 expression) and sorafenib-resistant (high mtTXNRD3 expression) cells was analyzed using Student t-test.