Plots of Maximum Increase in β-CTX and Concurrent Changes in P1NP, BSAP, and Osteocalcin
The ‘dots’ represent the means. The ‘whiskers’ represent the 25th and 75th percentiles. Baseline is defined as the last non-missing value prior to first dose of study drug.
β-CTX = β-C-terminal telopeptide; P1NP= procollagen type 1 amino-terminal propeptide; BSAP= bone-specific alkaline phosphatase