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Effects of P. americana seeds on serum levels of estradiol (a) and progesterone (b) and tissue levels of estradiol (c). Data are presented as mean ± SEM, n = 5, µµµp < 0.001 versus [NORMAL], ##p < 0.01, ###p < 0.001 versus [SHAM], and ∗∗∗p < 0.001 versus [ENDO + DW]. SHAM: sham-operated animals; ENDO: animals with endometriosis; DW: distilled water; LTZ: letrozole; EE: ethanol extract of P. americana seeds.
