Table 2.
Effects of the ethanol extract of P. americana seeds on the number of antral follicles, luteinized unruptured follicles, and corpora lutea in rat ovaries.
| Groups | Antral follicles | Corpora lutea | LUFs |
|---|---|---|---|
| [NORMAL] | 15 ± 0.894 | 38.4 ± 2.785µµµ | 0.2 ± 0.2 |
| [SHAM] | 5.6 ± 1.029µµµ | 21 ± 2.588µµµ | 0.4 ± 0.244 |
| [ENDO + DW] | 1.6 ± 0.509µµµ# | 11.4 ± 1.568µµµ## | 4 ± 0.316µµµ### |
| [ENDO + LTZ] | 4.4 ± 0.509µµµ | 15 ± 1.516µµµ | 3.8 ± 0.583µµµ### |
| [ENDO + EE12.5] | 4 ± 0.707µµµ | 15.4 ± 1.288µµµ | 0.6 ± 0.244∗∗∗ |
| [ENDO + EE25] | 4.6 ± 0.748µµµ | 18.2 ± 1.2µµµ∗ | 1.4 ± 0.4∗∗∗ |
| [ENDO + EE50] | 4.2 ± 0.583µµµ | 14.4 ± 2.111µµµ | 0.8 ± 0.374∗∗∗ |
Results are expressed as mean ± SEM, n = 5, µµµp < 0.001 versus [NORMAL]; ###p < 0.001, ##p < 0.01, and #p < 0.05, versus [SHAM]; ∗p < 0.05 and ∗∗∗p < 0.001 versus [ENDO + DW]. SHAM: sham-operated animals; ENDO: animals with endometriosis; DW: distilled water; LTZ: letrozole; EE: ethanol extract of P. americana seeds; LUFs: luteinized unruptured follicles.