Table 2.
| Examinations, baseline | PD patients (n = 21) | Healthy controls (n = 19) | p value |
|---|---|---|---|
| Arterial hypertension, yes/no | 11/10 | 9/10 | >0.999 |
| Orthostatic hypotension1, yes/no | 3/18 | 5/14 | 0.442 |
| Tympanic temperature, °C: mean ± SD | 36.7 ± 0.3 | 36.6 ± 0.2 | 0.195 |
| Subjective hyposmia, yes/no | 19/2 | 2/17 | <0.0001 |
| Olfactory function, Sniffin' sticks; median (IQR) | 7 (5.5–10) | 12 (11–14) | <0.0001 |
| Baseline temperature, 3rd finger distal phalanx, °C: mean ± SD | 27.8 ± 3.7 | 29.2 ± 3.1 | 0.1814 |
| Baseline temperature, 5th finger distal phalanx, °C: mean ± SD | 27.4 ± 3.7 | 28.9 ± 3.2 | 0.1749 |
| Thermal symmetry2, 1st finger distal phalanx, °C: median (IQR) | 0.22 (0.12–0.63) | 0.52 (0.32–1.0) | 0.029 |
| Thermal symmetry2, lower dorsal foot, °C: median (IQR) | 1.13 (0.49–1.98) | 0.46 (0.33–0.69) | 0.002 |
| Thermal symmetry2, 2nd toe, °C: median (IQR) | 0.55 (0.32–1.89) | 0.14 (0.03–0.63) | 0.012 |
1Orthostatic hypotension: decline of ≥20/10 in mmHg in systolic/diastolic blood pressure. 2Thermal symmetry = temperature difference between contralateral ROIs, calculated from all ROIs on trunk/extremities. Only ROIs with significant baseline symmetry differences are listed.