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. 2020 Jul 28;76(Pt 8):326–333. doi: 10.1107/S2053230X20009012

Figure 3.

Figure 3

Sequence and structural comparisons of RUN domains. (a) Sequence alignment of RUN domains. Secondary-structural elements are indicated above the alignments. The conserved residues are highlighted in red. The residues of Rab6IP1 that interact with Rab6 and those of RUSC2 that interact with Rab35 are highlighted in yellow and purple, respectively. (b) Superposition of RUN domains. The RUN domains of FYCO1, RPIPx (Kukimoto-Niino et al., 2006 ▸), Rab6IP1 (Recacha et al., 2009 ▸), NESCA (Sun et al., 2012 ▸) and RUSC2 (Lin et al., 2019 ▸) are shown in green, blue, yellow, red and purple, respectively. (c) Structural differences among the five RUN domains. Secondary-structural elements are indicated.