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Interaction surface of the RUN–small GTPase complex. (a) Crystal structures of the Rab6IP1–Rab6 and RUSC2–Rab35 complexes (Recacha et al., 2009 ▸; Lin et al., 2019 ▸). Rab6IP1, Rab6, RUSC2 and Rab35 are shown in yellow, red, purple and orange, respectively. (b) Electrostatic surface potentials of the five RUN domains. The electrostatic surface potential is coloured from −8 kT e−1 (red) to +8 kT e−1 (blue).
