Table 3. The interactions of GSH with conserved amino-acid residues in the G-site of GSTs.

Bound GSH	XacGST	StGST	hGSTT1	hGSTT2
Amine from glutamyl moiety	Glu67	Glu67	Glu66	Glu66
Carboxylate O atoms from glutamyl moiety	Ser68	Ser68	Ser67	Ser67
S atom from cysteinyl moiety	Ser12, Asn14	Ser10	—	Ser11, Arg107
Amide and carbonyl from cysteinyl moiety	Val55	Val53	—	Leu54
Carboxylate O atoms from glycyl moiety	Arg9, Gly36, Asn41	Arg7, Gly34, Asn39	His40, Arg234	His40, Lys41