Table 2.
Histologic Characteristics of the Study Population and the Derivation and Validation Cohorts
| Study population (N = 246), N (%) | Derivation cohort (N = 100), N (%) | Validation cohort (N = 146), N (%) | P valuea | |
|---|---|---|---|---|
| Steatosis | .44 | |||
| Grade 1 | 70 (28) | 26 (26) | 44 (30) | |
| Grade 2 | 139 (57) | 58 (58) | 81 (56) | |
| Grade 3 | 37 (15) | 16 (16) | 21 (14) | |
| Lobular inflammation | .18 | |||
| Score 0 | 41 (17) | 10 (10) | 31 (21) | |
| Score 1 | 163 (67) | 73 (73) | 90 (62) | |
| Score 2 | 38 (15) | 16 (16) | 22 (15) | |
| Score 3 | 4 (1) | 1 (1) | 3 (2) | |
| Ballooning | .41 | |||
| Score 0 | 56 (23) | 14 (14) | 42 (29) | |
| Score 1 | 116 (47) | 54 (54) | 62 (42) | |
| Score 2 | 74 (30) | 32 (32) | 42 (29) | |
| Fibrosis | .3 | |||
| 0 | 24 (10) | 9 (9) | 15 (10) | |
| 1 | 67 (27) | 20 (20) | 47 (32) | |
| 1a | 27 (11) | 10 (10) | 17 (11.4) | |
| 1b | 3 (1) | 2 (2) | 1 (0.6) | |
| 1c | 37 (15) | 8 (8) | 29 (19) | |
| 2 | 40 (16) | 21 (21) | 19 (13) | |
| 3 | 82 (34) | 35 (35) | 47 (33) | |
| 4 | 33 (13) | 15 (15) | 18 (12) | |
a
P value for the difference between the derivation and validation groups.