Fig. 1.

Expression level of hsa_circ_0000517 in HCC tissues and cells. a QRT-PCR was conducted to detect hsa_circ_0000517 expression in 50 paired HCC tissues and adjoining normal tissues. b High hsa_circ_0000517 expression and low hsa_circ_0000517 expression were divided according to the median of patients with HCC. c Kaplan–Meier curves and log-rank test were employed to determine the survival time of HCC patients with high hsa_circ_0000517 expression and low hsa_circ_0000517 expression. d QRT-PCR was employed to assess the resistance of hsa_circ_0000517 and RPPH1 to RNase R. e QRT-PCR was performed to evaluate hsa_circ_0000517 expression in HCCLM3, Huh7, and MHCC97-H, and THLE-2 cells. *P < 0.05