Fig. 3.

Histological sections of the bones and BM cellularity of the different groups tested. Representative cross-sections of tibia of mice at the termination of the follow-up stained with H&E to observe the degree of regeneration of the BM (a). A typical area in each bone section is further magnified. The difference in the cellularity of the BM in each group is demonstrated. Total BM cell counts obtained from the 4 long bones of all mice, frequency of HSCs, and total numbers of HSCs in the different groups are presented in (b–d), respectively