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. 2020 Aug 3;11:333. doi: 10.1186/s13287-020-01841-1

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© The Author(s) 2020

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 7 — Inflammatory infiltration and Runx2 expression in an experimental pulpitis model of rats after direct pulp capping with rDFSC-CM. A–C The degree of inflammatory infiltration in rats with experimental pulpitis in which the pulp was directly capped with rDFSC-CM for 24 h was determined by HE staining. A, A1 Blank control group (× 10). B, B1 The infiltration of inflammatory cell in the αMEM + LPS group is indicated by a black arrow (× 10). C, C1 rDFSC-CM + LPS group (× 4). Representative images of three independent experiments are shown. D–F The expression of Runx2 in an experimental pulpitis model in rats after direct pulp capping with rDFSC-CM for 7 days was revealed by immunofluorescence staining (× 20). D, D1 Blank control group. E, E1 αMEM + LPS group. Capillary dilatation is indicated by red arrows. F, F1 rDFSC-CM + LPS group. Some of the cells were positive for Runx2 (yellow arrows). Representative images of three independent experiments are shown