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. 2020 Aug 3;18:264. doi: 10.1186/s12955-020-01510-0

Table 4.

The weighted mean (95% confidence intervals (CIs)) for quality of life by SF36

Subgroups Number of studies (Sample Size) Weighted Mean (95% CI) Range Between subgroups Between groups
I2c (%) P heterogeneity Qd P heterogeneity
Minimum Maximum
Trans 0.000
 MTFa 3 (126) 62.47 (45.94, 79.00) 29.94 95.87 12.9 0.328 7.41
 FTMb 4 (507) 57.54 (42.24, 72.84) 27.29 87.86 0.0 0.401
Domains 9.49 0.000
 Physical 5 (633) 74.53 (59.13, 89.92) 49.00 92.70 65.9 0.004
 Social 5 (633) 59.57 (38.39, 80.75) 14.00 85.50 66.1 0.004
 Role physical 5 (633) 55.07 (43.52, 66.62) 49.10 84.70 0.0 0.817
 Role emotional 5 (633) 53.30 (40.22, 66.38) 42.42 83.00 0.0 0.746
 Mental health 5 (633) 57.88 (47.91, 67.84) 42.12 73.00 0.0 0.502
 Vitality 5 (633) 54.23 (44.27, 64.18) 46.22 63.91 0.0 0.951
 Body pain 5 (633) 59.62 (48.97, 70.27) 49.10 80.65 0.0 0.555
 General health 5 (633) 59.84 (49.63, 70.04) 47.76 77.10 0.0 0.544
Mean age 7.52 0.000
  ≤ 35 2 (407) 60.00 (44.36, 75.64) 49.05 79.40 11.0 0.338
 > 35 3 (226) 60.21 (43.88, 76.54) 46.99 78.15 3.0 0.378
Geographical eras 5.25 0.004
 USA 1 (376) 48.05 (34.33, 61.76)
 France 2 (164) 76.17 (53.60, 88.73) 74.00 78.15 0.0 0.990
 Belgium 1 (47) 79.40 (33.15, 87.43)
 Iran 1 (46) 66.19 (20.92, 89.78)
Overall 5 (633) 59.17 (48.59, 69.74) 46.99 79.40 0.0 0.487 10.97 0.0001

aMTF Male to Female, bFTM: Female to Male, cI2 I Square, dQ Cochran’s Q test