Table 4.
Unadjusted Risk-Related Driving Indicators by Tier 1 Drug Class: Mean (Standard Deviation)
| Drug Class (N Taking Drug) | Deceleration Ratea | p | Speeding Rateb | p | Right/Left turn Ratioc | p | |||
|---|---|---|---|---|---|---|---|---|---|
| Use of Drug: | No | Yes | No | Yes | No | Yes | |||
| Antihistamine (396) | 5.4 (6.2) | 5.7 (7.2) | .33 | 7.6 (16.4) | 9.27 (21.8) | .07 | .93(.13) | .95(.14) | .01 |
| Anti-infective (295) | 5.4 (6.4) | 5.5 (5.9) | .76 | 7.8 (17.6) | 8.2 (14.5) | .73 | .93(.13) | .94(.13) | .89 |
| Anti-neoplastic (111) | 5.4 (6.3) | 7.7 (17.1) | .10 | 7.7 (17.1) | 10.7 (21.1) | .07 | .94(.13) | .95(.14) | .42 |
| Autonomic drugs (648) | 5.3 (6.0) | 6.0 (7.6) | .01 | 7.6 (16.5) | 8.8 (19.7) | .12 | .93(.13) | .94(.13) | .41 |
| Blood formulation, coag, thrombosis (389) | 5.3 (6.3) | 6.0 (7.0) | .08 | 7.9 (17.7) | 7.2 (13.9) | .43 | .94(.13) | .94(.15) | .90 |
| Cardiovascular drugs (2146) | 5.5 (6.1) | 5.4 (6.5) | .69 | 8.3 (18.6) | 7.7 (16.8) | .43 | .94(.13) | .94(.13) | .80 |
| CNS agents (2051) | 5.2 (6.3) | 5.5 (6.4) | .23 | 7.1 (16.0) | 8.1 (17.8) | .13 | .93(.14) | .94(.13) | .23 |
| Electrolytic, Caloric and Water Balance (1601) | 5.8 (7.2) | 5.1 (5.6) | <.01 | 8.7 (18.7) | 7.1 (16.0) | .01 | .94(.13) | .94(.13) | .86 |
| Respiratory Tract Agents (105) | 5.4 (6.4) | 6.0 (6.2) | .34 | 7.6 (17.2) | 9.8 (20.0) | .23 | .94(.13) | .93(.13) | .81 |
| Eye Ear Nose and Throat Preparations (718) | 5.2 (6.1) | 6.0 (7.1) | <.01 | 7.9 (17.0) | 7.7 (18.0) | .82 | .93(.13) | .94(.13) | .13 |
| Gastrointestinal drugs (944) | 5.3 (6.4) | 5.6 (6.4) | .21 | 7.6 (16.4) | 8.4 (19.0) | .25 | .93(.13) | .94(.13) | .20 |
| Hormones and Synthetic Substitutes (1300) | 5.1 (6.0) | 5.9 (6.8) | <.01 | 7.4 (16.0) | 8.4 (18.7) | .10 | .93(.13) | .94(.13) | .17 |
| Local anesthetics (23) | 5.4 (6.2) | 10.0 (17.6) | <.01 | 7.8 (17.2) | 11.6 (24.2) | .30 | .94(.13) | .96(.14) | .47 |
| Skin and Mucous Membranes (484) | 5.3 (6.1) | 6.0 (7.6) | .03 | 7.7 (16.9) | 8.6 (18.8) | .30 | .93(.13) | .94(.13) | .45 |
| Smooth Muscle Relaxants (89) | 5.4 (6.4) | 5.5 (5.1) | .86 | 7.9 (17.4) | 6.8 (13.9) | .55 | .94(.13) | .94(.13) | .58 |
| Vitamins (1899) | 5.6 (6.7) | 5.4 (6.2) | .41 | 8.3 (18.6) | 7.6 (16.5) | .27 | .94(.13) | .94(.13) | .91 |
| Miscellaneous agents (371) | 5.4 (6.5) | 5.5 (5.6) | .85 | 7.6 (16.7) | 9.5 (20.5) | .05 | .93(.13) | .95(.13) | .10 |
a Number of high deceleration (≥0.35 g) events events per 1000 miles driven
b Number of speeding (> 80 mph) events per 1000 miles driven
c Ratio of right turns to left turns; a higher mean ratio is indicative of possible reluctance to make left turns against oncoming traffic