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. 2020 Jun 25;61(8):1161–1167. doi: 10.1194/jlr.R120000922

TABLE 1.

Effects of age on LPL activity in rats

Tissue Strain Relevant Observation Reference
Adipose tissue Sprague-Dawley Increasing fasted LPL activity with age (2, 12, 24 months) (14)
No differences in fasted LPL activity at 40 days, 100 days, and 1 year of age (15)
Increased fed LPL activity (compared with fasting) at 40 days of age, but no difference between fasting and fed activity at 100 days or 1 year (15)
Fisher-344 Decreasing fasted LPL activity with age (2, 12, 24 months) (14)
Decreasing fasted LPL activity with age (6, 12, 15, 18, 21, and 24 months) (16)
Wistar Increased LPL activity at 15 months compared with 3 months (feeding state not specified) (22)
Cardiac tissue Sprague-Dawley No change in LPL activity with age (14)
Fisher-344 No change in LPL activity with age (14)
Decreasing fasted LPL activity with age (6, 12, 15, 18, 21, and 24 months) (16)
Diaphragm muscle Sprague-Dawley Decreased fasted LPL activity in 12- and 24-month-old rats compared with 2-month-old animals (14)
Fisher-344 No change in LPL activity with age (14)
Decreasing fasted LPL activity with age (6, 12, 15, 18, 21, and 24 months) (16)
Skeletal muscle Fisher-344 Decreased LPL activity in 24-month-old rats compare with 2-month-old animals in soleus but not tibialis anterior muscles (feeding state not specified) (23)
Fisher-344 × Brown Norway Decreased LPL activity in 31-month-old rats compare with 18-month-old animals in soleus but not tibialis anterior muscles (feeding state not specified) (23)