TABLE 2.

CE transfer between lipoproteins by different CETPs: net mass transfer

CETP	Net CE Transfer
	LDL to VLDL	HDL to VLDL	Total Net CE to VLDL	HDL to VLDL/LDL to VLDL
Hamster	439 ± 16	1,094 ± 17	1,533 ± 40	2.49 ± 0.10
Human	354 ± 23a	1,019 ± 17a	1,373 ± 55a	2.88 ± 0.19a
H232A	327 ± 19a	943 ± 28a,b	1,270 ± 56a,b	2.89 ± 0.19a

VLDL, LDL, and HDL were combined in a physiologic ratio and incubated with the indicated CETP. Shown are the rates of net CE transfer from the indicated donor to the indicated acceptor mediated by CETP. CE net transfer was calculated from the difference between unidirectional transfers reported in Table 1 (for example, LDL to VLDL minus VLDL to LDL). H232A is a mutated form of human CETP. The values shown are in nanograms of CE per hour. Mean ± SD, n = 6.

^aP < 0.01 versus hamster.

^bP < 0.01 versus. human.