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. 2020 Jun 2;61(8):1203–1220. doi: 10.1194/jlr.RA120000781

TABLE 2.

Circulating ANGPTL3/8 and ANGPTL4/8 are highly correlated with metabolic syndrome markers

Phenotype ANGPTL3/8 ANGPTL4/8
R-Value P R-Value P
TG 0.485 <0.0001 0.261 <0.0001
HDL-C −0.279 <0.0001 −0.247 <0.0001
LDL-C 0.218 <0.0001 0.062 0.24 (NS)
Total cholesterol 0.233 <0.0001 0.072 0.18 (NS)
BMI 0.484 <0.0001 0.377 <0.0001
Waist-hip ratio 0.351 <0.0001 0.240 <0.0001
Fasting glucose 0.282 <0.0001 0.215 <0.0001
Fasting insulin 0.635 <0.0001 0.473 <0.0001
Systolic blood pressure 0.187 0.0005 0.196 0.0003
Diastolic blood pressure 0.286 0.0002 0.234 <0.0001

ANGPTL3/8 and ANGPTL4/8 complexes were measured in fasting serum samples from SCARF subjects (n = 352), and their associations with various metabolic parameters were assessed.