Table 1.
Thromboprophylaxis Regimes from Studies Reporting the Incidence of VTE in Patients with COVID-19 Infection
| Study | Heparin | Dose | Patient Cohort | ||
|---|---|---|---|---|---|
| Tang and colleagues (4) | Enoxaparin | 40–60 mg once daily | ITU | ||
| UFH | 10–15,000 u once daily | ||||
| Klok and colleagues (5) | Nadroparin | 2,850 IU once daily* increased in some to 5,700 IU twice daily later in study† | ITU | ||
| Helms and colleagues (6) | Not stated | Prophylactic/therapeutic | ITU | ||
| Middeldorp and colleagues (7) | Nadroparin | 2,850 IU once daily increased to twice daily later in study* | ITU | ||
| Nadroparin | 2,850 IU once daily | Ward |
Definition of abbreviations: COVID-19 = coronavirus disease; ITU = intensive therapy unit; UFH = unfractionated heparin; VTE = venous thromboembolism.
5,700 IU once daily for patients weighing more than 100 kg.
For patients weighing more than 100 kg, the dose was increased to 5,700 IU twice daily.