Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Aug 1;34(15-16):1065–1074. doi: 10.1101/gad.330050.119

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2020 Björkman et al.; Published by Cold Spring Harbor Laboratory Press

This article, published in Genes & Development, is available under a Creative Commons License (Attribution 4.0 International), as described at http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Figure 6. — Cartoon showing our model of the role of RTEL1 and Poldip3 in R-loop resolution. RTEL1 associates with the replisome, here represented by Polδ (gray) and PCNA (yellow) via Poldip3 and/or PCNA, as it replicates DNA. As the replication fork encounters the transcription machinery, RTEL1 might resolve R-loops that block the replication fork and/or the R-loops provoked by stalling of replication (shown by arrows from RTEL1). (RNAPII) RNA polymerase II. The black lines represent single-stranded DNA and the red lines depict RNA. The big arrow indicates the direction of the replication fork.