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. 2020 Jul;30(7):1000–1011. doi: 10.1101/gr.261537.120

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© 2020 Krieger et al.; Published by Cold Spring Harbor Laboratory Press

This article is distributed exclusively by Cold Spring Harbor Laboratory Press for the first six months after the full-issue publication date (see http://genome.cshlp.org/site/misc/terms.xhtml). After six months, it is available under a Creative Commons License (Attribution-NonCommercial 4.0 International), as described at http://creativecommons.org/licenses/by-nc/4.0/.

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Figure 4. — Regulatory dynamics vary mainly in trans. (A) Defining trans-varying genes. Plotted are R^C scores between hybrid alleles as a function of R^C scores between species for all genes. Black line is x = y. Genes in the red rectangle vary in trans (184 genes). Indicated genes vary in trans (VTC3, CHA1) and in cis (LSO2) and are discussed in subsequent figures. Color represents density. (B) Defining cis-varying genes. Plotted are R^C scores between hybrid alleles as a function of R^C scores of the mean hybrid data set control. Genes in the red rectangle vary in cis (106 genes).