Figure 2.

Box plots of activated whole‐blood IL‐2 (a) and IFN‐γ (b) RNA expression presented as a percentage of untreated activated baseline samples, in which the untreated activated baseline samples represent 100% cytokine production, from six healthy Walker hounds. The effects of cyclosporine and the subsequent recovery of T‐cell cytokine RNA expression over 7 days following cessation of cyclosporine are presented. The line within each box denotes the median, box edges represent the first and third quartiles, and whiskers extend to maximum and minimum values. Less than 5% of pre‐treatment values is clinically categorized as marked suppression (IL‐2 = interleukin‐2, IFN‐γ = interferon‐gamma, WO = washout [recovery period])