Table 1.
Anti–HIV evaluation of the extracts obtained from A. campestris. MT–2 cells were infected with a recombinant HIV–1 (NL4.3–Ren. 100.000 RLUs or 20 ng p24/well) in the presence of different concentrations of the extracts. Results were obtained 48 h later in a luminometer using the Renilla assay system. IC50 and CC50 were calculated using Prism v8.0 (GraphPad Software). Hexane EE: hexane extract from ethanolic extract. DCM EE: Dichloromethane extract from ethanolic extract. Ethanol EE: Ethanol extract from ethanolic extract. Aqueous EE: Aqueous extract from ethanolic extract. IC50: Inhibitory concentration 50%; CI95%: Confidence interval 95%.
| IC50 μg/mL HIV (CI95%; R2) | |
|---|---|
| Ethanol extract (EE) | 28.57 (5.19–790.8; 0.8021) |
| Aqueous extract (AE) | 88.17 (30.17–713.3; 0.8353) |
| Hexane EE | 63.17 (19.22–649.2; 0.8261) |
| DCM EE | 23.06 (11.38–54.68; 0.9863) |
| Ethanol EE | 42.68 (13.37–84.58; 0.7337) |
| Aqueous EE | 98.86 (48.90–275.4; 0.9201) |