Table 2.
Anti–HIV evaluation of the fractions obtained from A. campestris. MT–2 cells were infected with a recombinant HIV–1 (NL4.3–Ren. 100.000 RLUs or 20 ng p24/well) in the presence of different concentrations of the 18 fractions. Results were obtained 48 h later in a luminometer using the Renilla assay system. IC50 were calculated using Prism v8.0 (GraphPad Software). IC50: Inhibitory concentration 50%; CI95%: Confidence interval 95%.
Fraction | IC50 μg/mL |
---|---|
1 | >50 |
2 | >50 |
3 | 29.3 (21.65–39.52; 0.7849 |
4 | 23.5 (16.50–33.36; 0.8272) |
5 | 7.6 (5.397–10.80; 0.6226) |
6 | 12.9 (8.40–9.70; 0.6927) |
7 | 24.7 (14.51–42.20; 0.6444) |
8 | >25<50 |
9 | >50 |
10 | 8.0 (4.58–14.10; 0.7053) |
11 | 4.9 (3.09–7.8; 0.7296) |
12 | 7.7 (4.24–14.15; 0.6695) |
13 | 8.2 (5.01–13.56; 0.7467) |
14 | 20.5 (6.60–63.64; 0.5242) |
15 | 1.5 (1.03–2.17; 0.7382) |
16 | 7.9 (4.89–12.73; 0.7495) |
17 | 12.0 (7.88–18.41; 0.7999) |
18 | 20.1 (14.75–27.24; 0.8385) |