Figure 1.
Median concentrations of adipokines, and longitudinal change from 10–14 GWs to 15–26 GWs expressed as ng/mL (IL-6 expressed as pg/mL) according to gestational age intervals among women with GDM (solid red line) and their matched control subjects (dashed black line). *P<0.05; **p<0.01; ***p<0.001 for case-control comparisons obtained by mixed-effect linear regression models accounting for matched case-control pairs at each gestational age interval. P∆=p < 0.05 for case-control comparison of change in adipokine concentrations from 10–14 GWs to 15–26 GWs obtained by mixed-effect linear regression models accounting for matched case-control pairs. FABP-4, fatty acid binding protein 4; GDM, gestational diabetes mellitus; GW, gestational week; HMW-adiponectin, high-molecularweight-adiponectin; IL-6, interleukin-6; sOB-R, soluble leptin receptor.