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![Multinuclear hydrogen 1 and 13C MR images of the right breast at baseline (top) and after one cycle of neoadjuvant chemotherapy (bottom). (a) Coronal summed hyperpolarized [1-13C]-pyruvate and (b) [1-13C]-lactate signal overlaid on unenhanced T1-weighted images. (c) Coronal dynamic contrast-enhanced MR image obtained 150 seconds after contrast agent injection and (d) overlaid transfer constant (Ktrans) map.](https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f2ef/7983752/ce7b86435182/rycan.2020200017.fig1d.jpg)
Multinuclear hydrogen 1 and 13C MR images of the right breast at baseline (top) and after one cycle of neoadjuvant chemotherapy (bottom). (a) Coronal summed hyperpolarized [1-13C]-pyruvate and (b) [1-13C]-lactate signal overlaid on unenhanced T1-weighted images. (c) Coronal dynamic contrast-enhanced MR image obtained 150 seconds after contrast agent injection and (d) overlaid transfer constant (Ktrans) map.
