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. Author manuscript; available in PMC: 2020 Aug 3.
Published in final edited form as: Curr Top Dev Biol. 2015 Oct 6;115:459–492. doi: 10.1016/bs.ctdb.2015.07.003

Figure 2.

Figure 2

Craniofacial features of the RASopathies. The RASopathies are caused by mutations in genes encoding different proteins in the RAS pathway and have both unique and overlapping craniofacial characteristics. (A) Frontal and profile photographs of a 7-year-old male and (B) 21-year-old female with Noonan syndrome (NS), (C) a 20-year-old male and (D) 23-year-old female with Costello syndrome (CS), and (E) a 15-year-old male and (F) 15-year-old female with cardio-facio-cutaneous syndrome (CFC).