Table 3.

Comparison of clinical presentation between pituitary apoplexy cases (n = 121) and controls (n = 242)

Symptom/sign	Pituitary apoplexy (n = 121)		control (n = 242)		P
Symptom/sign	n	%	n	%	P
Headache	87	71.9	130	53.7	0.001^*
Vomiting	23	19.0	14	5.80	0.000^*
Fever	3	2.5	5	2.10	0.800^*
Visual impairment	80	66.1	155	64.0	0.698^*
Diplopia	2	1.7	7	2.90	0.474^*
Ablepsia	12	10.0	11	4.50	0.045^*
Visual field defect	51	50.4	124	51.20	0.882^*
Acromegaly	5	4.1	18	7.40	0.223^*
Cushingoid appearance	0	0	4	1.7	0.356^†
Sexual hypoactivity^b	0	0	3	1.2	0.463^†
Hypopituitarism	20	16.5	28	11.6	0.189^*
Hypothyroidism	32	26.45	31	12.81	0.001^*
Amenorrhea^a	16	15.84	72	12.57	0.542^*
Altered menstrual cycle^a	14	11.57	26	10.74	0.406^*
Galactorrhoea^a	19	15.70	23	9.50	0.026^*
Gynecomastia^b	0	0	0	0	–

*Pearson’s chi-squared test

^aThese calculations include only women

^†Pearson’s statistic with a continuity correction

^bThese calculations include only men