Table 1.
Clinical factors | Univariate | P | Multivariate | P | ||||
---|---|---|---|---|---|---|---|---|
HR | 95%CI | HR | 95%CI | |||||
Lower | Upper | Lower | Upper | |||||
Age at diagnosis | 1.044 | 1.026 | 1.062 | < 0.0001 | 1.011 | 0.993 | 1.029 | 0.240 |
Gender (male) | 1.162 | 0.792 | 1.704 | 0.443 | ||||
IDH1 status (mutation) | 0.335 | 0.219 | 0.511 | < 0.0001 | 0.932 | 0.544 | 1.597 | 0.799 |
High HOXC8 expression | 1.545 | 1.397 | 1.709 | < 0.0001 | 1.247 | 1.110 | 1.402 | < 0.0001 |
Grade (high grade) | 3.960 | 2.960 | 5.299 | < 0.0001 | 3.176 | 2.307 | 4.371 | < 0.0001 |
TCGA subtype (mesenchymal type) | 1.605 | 1.362 | 1.890 | < 0.0001 | 1.048 | 0.866 | 1.267 | 0.631 |
IDH1: isocitrate dehydrogenase 1; CGGA: Chinese Glioma Genome Atlas; TCGA: The Cancer Genome Atlas; CI: Confidence Interval