Table 5.
Multivariable analysis of favourable neurological outcome in all CCPR cases and in patients divided by NLT
| Variables | All cases (n = 2278) | P value | OR (95% CI) | NLT > 30 min (n = 1362) | P value | OR (95% CI) | NLT > 45 min (n = 719) | P value | OR (95% CI) |
|---|---|---|---|---|---|---|---|---|---|
| Age (years) | 77 (66–85) | < 0.001 | 0.944 (0.932–0.956) | 78 (68–85) | 0.006 | 0.958 (0.929–0.988) | 78 (78–85) | 0.017 | 0.934 (0.884–0.988) |
| Male (%) | 1457 (64%) | 0.553 | 1.121 (0.768–1.637) | 848 (62%) | 0.578 | 0.758 (0.285–2.017) | 467 (65%) | 0.662 | 0.660 (0.103–4.245) |
| BCPR (%) | 991 (44%) | < 0.001 | 3.421 (2.396–4.884) | 605 (44%) | 0.265 | 1.695 (0.670–4.290) | 313 (44%) | 0.246 | 0.256 (0.025–2.564) |
| SR (%) | 463 (20%) | < 0.001 | 4.425 (3.037–6.447) | 213 (16%) | < 0.001 | 11.133 (4.122–30.067) | 102 (14%) | 0.011 | 9.996 (1.684–59.322) |
| NLT (min)a | 36 (21–50) | < 0.001 | 0.858 (0.843–0.872) | 47 (38–57) | 0.029 | 0.951 (0.910–0.995) | 56 (50–63) | 0.274 | 0.940 (0.841–1.050) |
| CPC 1–2 | 390 (17%) | – | – | 20 (2%) | – | – | 6 (1%) | – | – |
Values are median (interquartile range) or n (%) of cases
CCPR conventional cardiopulmonary resuscitation, NLT no and low-flow time, OR odds ratio, CI confidence interval, BCPR bystander cardiopulmonary resuscitation, SR shockable rhythm, CPC cerebral performance category
aDefined as the interval from witnessed OHCA to start of reperfusion (start of extracorporeal membrane oxygenation for ECPR or return of spontaneous circulation for CCPR)