Table 3.

Relation of the GDF-15 level and MACEs in univariate and multivariate survival analysis

	Independent predictors of major adverse cardiac events
	Univariate models			Multivariate models
	HR	95% CI	P	HR	95% CI	P
Age	1.02	1.013−1.026	0.00	1.02	1.009−1.022	0.00
Sex	0.00	0.001−0.028	0.00	0.01	0.001−0.057	0.00
Smoking	1.10	0.933−1.296	0.23	–	–	–
BMI	0.98	0.959−1.000	0.05	1.00	0.977−1.020	0.89
Hypertension	1.03	0.646−0.880	0.00	0.82	0.703−0.967	0.02
Hyperlipidemia	1.15	0.98–1.34	0.09	–	–	–
DM	0.79	0.680–0.911	0.00	0.89	0.767–1.032	0.14
GDF-15 ≤ 1200 ng/L	1.05	0.87–1.44	0.16	–	–	–
1200 < GDF-15 ≤ 1800 ng/L	1.09	0.90–1.65	0.08	–	–	–
GDF-15 > 1800 ng/L	1.92	1.37–2.52	< 0.001	1.74	1.44–2.02	< 0.001